![Cyclosporin A Mouse Monoclonal Antibody [Clone ID: 4A3 (CSZ.22)] - 200 ug](/web/image/product.product/8487/image_1024/%5B0937-BM941%5D%20Cyclosporin%20A%20Mouse%20Monoclonal%20Antibody%20%5BClone%20ID:%204A3%20%28CSZ.22%29%5D%20-%20200%20ug?unique=acbb953)
| Clone Name | 4A3 (CSZ.22) |
| Applications | ELISA |
| Recommended Dilution | ELISA. |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Cyclosporin A conjugated to an HMW carrier |
| Specificity | This antibody recognizes Cyclosporin A, a widely-used immunosuppressant drug from the fungus Tolypocladium inflatum. |
| Formulation | PBS State: Purified State: Liquid (0.45 µm filtered) purified IgG fraction Preservative: 0.09% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Background | Cyclosporin is used to prevent rejection following solid organ and bone marrow transplantation . It has been estimated that cyclosporine is given to more than 90% of children who have received a kidney transplant in the United States. In addition, the ability of cyclosporin to inhibit T-cell activation has been shown to have a role in the treatment of diseases such as nephrotic syndrome, refractory Crohn's disease and ulcerative colitis, biliary cirrhosis, aplastic anemia, rheumatoid arthritis, myasthenia gravis, and dermatomyositis. |