AapCas12b Active recombinant protein - 0.05 mg

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1,095.48 1095.48 USD 1,095.48

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    Host: E. coli

    Purity: >75%

    Form: Liquid

    Buffer: 50mM sodium phosphate, pH7.5, 300mM NaCl, 1mM DTT, 10% glycerol.

    Concentration: 2.0 pmol/ul (lot specific)

    Species: Alicyclobacillus acidiphilus

    Scientific Background: CRISPR (clustered regularly interspaced short palindromic repeat) and their CRISPR-associated (Cas) proteins constitute the adaptive immune system in bacteria. This system has been redesigned to create an exemplary genome editing tool for application to RNA-based therapeutics development. AapCas12b belongs to the type V CRISPR effector, CRISPR-Cas12b/C2c1, and due to its thermostability, it can be used in a wide range of biomedical applications including loop-mediated isothermal amplification (LAMP), mammalian genome editing, and gene activation.

    Preparation and Storage: Ships on dry ice.

    Aliquot into smaller quantities after centrifugation and store at –70°C. Avoid repeated handling and multiple freeze/thaw cycles.