Anti-CDX-2

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1,535.10 1535.1000000000001 USD 1,535.10

1,505.00 €

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    Intended Use: This antibody is designed for the
    specific localization of CDX2 in formalin-fixed, paraffinembedded (FFPE) tissue sections. Evaluation must be performed
    by a qualified pathologist. 

    Summary and Explanation: CDX2, a member of the caudal-related homeobox family, is an
    intestine-specific transcription factor that regulates both
    proliferation and differentiation in intestinal epithelial cells. It
    plays an important role in triggering cells towards the
    phenotype of differentiated villus enterocytes as well as in the
    maintenance of the phenotype. Clone CDX2-88 reacts with a
    conserved epitope of the 40kD CDX2 protein localized in the
    nucleus. It exclusively marks nuclei of colonic epithelial cells
    and colorectal cancers on formalin-fixed, paraffin-embedded
    tissue sections. 

    Storage and Handling: Store at 2-8°C. Fresh dilutions, if required, should be prepared
    prior to use and are stable and steady for up to one day at room
    temperature (20-26°C). Diluted antibody preparations can be
    refrigerated or frozen for extended shelf life.